Relieve painful and heavy legs with Venixxa
Venixxa helps relieve signs and symptoms associated with mild-to-moderate chronic venous disease
Answer 5 short questions to assess your symptoms and risk factors
Are you experiencing painful, heavy, or swollen legs?
If so, you may be suffering from chronic venous disease, a progressive* disease that needs to be treated.
Chronic venous disease affects the valves in your veins, whose primary function is to prevent blood from flowing backwards. As a result, damaged valves cause blood to flow back into the veins, pooling in the lower leg. This increased fluid can cause pain, edema and a sensation of heaviness which can worsen over time.
If you think you are suffering from chronic venous disease, it is important to seek treatment.
Healthy Veins
Healthy veins have small valves which prevent blood from flowing backwards.
Unhealthy Veins
When the internal walls of the veins are damaged, and these valves don’t work as well, blood can flow back into the veins, resulting in pooling in the lower leg and leading to dilated veins and uncomfortable symptoms that can worsen over time.
Symptoms of Poor Blood Flow
A range of signs and symptoms can point to poor blood flow in the legs. If you’ve been experiencing any of the following symptoms in your legs or ankles, you should seek treatment as they can worsen over time.
Heavy, Painful or Swollen Legs
Tired Legs
Leg pain
Spider or Varicose veins
Looks familiar?
Seek treatment at the first sign of symptoms as chronic venous disease can worsen over time. If you regularly suffer from at least one of the symptoms of chronic venous disease, take the Veinscore Assessment and speak to your pharmacist or physician about the best treatment for you.
Treat Your Symptoms Early
Painful, heavy and swollen legs can be early signs of chronic venous disease. Left untreated, chronic venous disease can progress* and worsen over time, making existing symptoms worse and new ones appear.
Leg pain, heaviness, and swelling are warning signs of chronic venous disease. If untreated, symptoms of chronic venous disease may increase in severity, leading to spider veins, varicose veins, and leg ulcers*.
If you are experiencing any of the signs of chronic venous disease, it is important to speak to your pharmacist or physician about treatment options.
The different stages of disease are described as grades 0-6 depending on the severity of the symptoms as shown here:
Stage 0
Heavy, Painful Legs
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Stage 0
Heavy, Painful Legs
The first stage, with no visible signs of venous disease. However, damage may already be starting to accumulate inside the veins. This leads to venous reflux and is why you should start treating, even if your only symptoms are heavy and painful legs.
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Stage 1
Spider/Varicose Veins
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Stage 1
Spider/Varicose Veins
Ignoring the first symptoms can cause the condition to worsen, leading to broken blood vessels or spider veins and visible veins. They aren’t usually painful, but are an important indicator of leg vein problems. It’s important not to ignore this early sign as the condition can rapidly progress*.
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Stage 2
Visible varicose veins
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Stage 2
Visible varicose veins
Left untreated, stage 1 turns to stage 2 with the veins becoming unusually dilated, stretched out and sinuous. These obvious, bulging veins on the legs and ankles are a clear sign of chronic venous disease.
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Stage 3
Swelling of the ankle and leg
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Stage 3
Swelling of the ankle and leg
Edema (swelling) may appear in stage 3, it is caused by increased pressure and leakage as a result of further deterioration of the venous walls and valves.
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Stage 4
Skin changes
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Stage 4
Skin changes
Continued poor circulation can lead to stage 4, characterized by darkening of the skin around your ankles (hyperpigmentation), redness, dryness, itchiness (venous eczema), hardening of soft tissues and the development of whitish patches.
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Stage 5
Healed ulcers
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Stage 5
Healed ulcers
Stage 5 is defined by the presence of open but healed areas of skin called ulcers. These can be painful and affect your quality of life, making it difficult to move around.
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Stage 6
Active ulcers
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Stage 6
Active ulcers
If you reach this stage, you will have open wounds called ulcers on your legs. Internally, at this stage, there is more deterioration in circulation and increased leakage in the capillaries.
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If you are experiencing any of the signs of chronic venous disease, it is important to speak to your pharmacist or physician about treatment options
*For information only. Venixxa does not treat all stages of CVD
By recognizing the symptoms and taking action, you can significantly lessen the impact on your day-to-day life.
RISK FACTORS YOU CAN CONTROL
Standing/sitting for long periods
Being overweight
RISK FACTORS YOU CAN’T CONTROL
Age
Gender
Genetics
Risk factors for chronic venous disease
There are several key risk factors for chronic venous disease, some of which may be beyond your control, but others you can take steps to modify. 1
Women are typically more at risk. Family history, as well as simply growing older, can increase your chances of developing symptoms.
Lifestyle factors you can take steps to negate, such as being overweight and inactive, can also increase your risk of developing problems with your veins. Those who stand or sit as part of their occupations, such as nurses, teachers and those in the service industry, are particularly at risk.
Don’t Let Your Legs Hold You Back.
1 tablet of Venixxa twice daily, midday and evening, with meals, or as directed by a healthcare practitioner. Use for a minimum of 2 months to see beneficial effects. If response is inadequate or unsatisfactory after 2 months, consult a health care practitioner as edema may have alternative causes. For use beyond 2 months, consult a healthcare practitioner.
Advice for Healthy Legs
By incorporating simple habits into your daily routine and maintaining a healthy lifestyle, you can help protect your legs from the discomfort caused by increased fluid in your legs and the damage this can cause to veins over time:
Stay active
Regular exercise helps improve circulation and tone the muscles in your legs.
Wear compression stockings
Compression stockings have a higher pressure gradient at the ankle which gradually decreases towards the top of the leg. They will counteract gravity and allow your body to better return blood from the legs to the heart.
Maintain a healthy weight
Keep a close eye on your weight as obesity can contribute to blocked or weakened valves in leg.
Avoid high heels
Choose a medium heel over flat or high-heeled shoes to encourage lower leg activity.
Wear loose clothing
Avoid tight clothing which can restrict blood flow in the legs and exacerbate the risk of chronic venous disease.
Stay cool
Veins dilate in the heat which can cause blood to pool and contribute to your legs feeling heavy and tired.
Move regularly
Avoid sitting or standing for too long to prevent blood pooling in your leg veins, and help blood flow to the heart.
Elevate your legs
Raise your legs and avoid crossing them to help blood flow towards the heart when relaxing.
In addition to lifestyle modifications, topical creams and gels can be used for symptom relief, and medical procedures can treat the advanced condition.
Frequently Asked Questions
If you think you are suffering from this progressive* condition, speak with a healthcare practitioner about the best treatment for you.
What is Venixxa recommended for?
Venixxa is an oral treatment that helps to relieve the signs and symptoms of mild-to-moderate chronic venous disease, such as varicose and spider veins, leg pain and the sensation of heavy legs. It also helps to reduce lower leg edema associated with the condition.
Do I need a prescription for Venixxa?
No. Venixxa is available over the counter at the pharmacy. If you cannot find it, your pharmacist can order it for you. Click here to find where it is available in your area.
How does Venixxa work?
Venixxa has a dual mechanism of action; its anti-inflammatory venoprotective action protects the capillaries or tiny blood vessels which improves microcirculation, and venous tone, in order to help relieve chronic venous disease symptoms such as heavy, painful and swollen legs 2
What is Venixxa?
Venixxa’s active ingredient is a micronized purified flavonoid fraction (MPFF). It is composed of citrus bioflavonoids, containing 90% diosmin and 10% other flavonoids expressed as hesperidin.
What does micronized mean?
Micronized means that a substance has been broken into very small particles for more effective absorption
How often do I take Venixxa for chronic venous disease?
Take 1 tablet of Venixxa twice daily, midday and evening, with meals, or as directed by a healthcare practitioner. Use for a minimum of 2 months to see beneficial effects. If response is inadequate or unsatisfactory after 2 months, consult a health care practitioner as edema may have alternative causes. For use beyond 2 months, consult a healthcare practitioner.
How long should I take Venixxa for?
Venixxa is a continuous treatment for chronic venous disease, an ongoing progressive condition. It is recommended that you continue to take Venixxa unless otherwise directed by your healthcare practitioner. For use beyond 2 months, consult a healthcare practitioner
I take a lot of medication, can Venixxa be taken with other medications?
I take a lot of medication, can Venixxa be taken with other medications?
Safety Information:
Venixxa - Safety Information
This product may not be suitable for you. Always read and follow the label and package insert carefully. Do not use Venixxa if you are pregnant or breastfeeding. If you are taking prescription medication, consult a healthcare practitioner prior to use. Consult a healthcare practitioner if chronic venous disease symptoms persist or worsen. If you suffer or experience inflammation of the skin, thrombophlebitis or subcutaneous induration, severe pain, ulcers, sudden swelling of one or both legs, cardiac or renal insufficiency or disorder, consult a healthcare practitioner.
Adverse Reactions
Hypersensitivity/allergy, gastrointestinal discomfort, dizziness, headaches, malaise and skin reactions have been known to occur; in which case, discontinue use and consult a healthcare practitioner.
References:
- Adapted from Nicolaides A, Kakkos S, Baekgaard N, and al. Management of chronic venous disorders of the lower limbs. Guidelines according to scientific evidence. Part I. Int Angiol. 2018;37(3):181-254.
- Katherine A. Lyseng-Williamson and Caroline M. Perry. Micronised Purified Flavonoid Fraction A Review of its Use in Chronic Venous Insufficiency, Venous Ulcers and Haemorrhoids
*For information only. Venixxa does not treat all stages of chronic venous disease.
2025